Main description:

Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders.

This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Contents:

G-protein-Coupled Receptor Signaling.- Implication of G-proteins in Cardiovascular Disease.- ?-Adrenoceptor-Linked Signal Transduction Mechanisms in Congestive Heart Failure.- Cardiac G?s and G?i Modulate Sympathetic Versus Parasympathetic Mechanisms in Hyperhomocysteinemia.- The Role of the Beta-Adrenergic Signal Transduction Pathway in Myocardial Protection.- Angiotensin II Signaling in Vascular Physiology and Pathophysiology.- Angiotensin II Signaling: Cell Growth and Apoptosis.- Redox Signaling.- Thioredoxin Signaling in the Ischemic Heart.- Relationship Between Redox Regulation and ?-Adrenergic Responses in the Heart.- Role of Hyperglycemia and Redox-Induced Signaling in Vascular Complications of Diabetes.- Methylglyoxal and Insulin Resistance.- Growth Factor Signaling.- Role of Growth Factor Receptor Transactivation in Vasoactive Peptide-Induced Signaling Pathways in Vascular Smooth Muscle Cells.- Identifying the Cellular and Molecular Events Associated with the Divergent Phenotypes of Cardiac Hypertrophy.- Regulatory Role of TGF-? in Cardiac Myofibroblast Function and Post-MI Cardiac Fibrosis: Key Roles of Smad7 and c-Ski.- The Signaling Duel Between Virus and Host: Impact on Coxsackieviral Pathogenesis.- Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease.- VEGF Signaling: A Therapeutic Target for Cardiovascular Disease.- Myristoyl-CoA: Protein N-Myristoyltransferase and Myristoyl-CoA Binding Protein from Bovine Cardiac Muscle.- Calcium Signaling.- Ca2+/Calmodulin-Dependent Protein Kinase II Signaling in Vascular Smooth Muscle.- The KCa3.1 Channel in Endothelial Cells as New Target for an EDHF-Based Control of Vascular Tone: From Structure to Regulation and Pharmacological Properties.- Adipokine Signaling.- Leptin Signaling in the Cardiovascular System.- AMPK Regulation of Cardiac Metabolism in Heart Disease.