Main description:

This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.

Contents:

Chapter 1. Introduction and Principles of Pharmacogenomics and Precision medicine.- Chapter 2. Pharmacogenomics in Cardiovascular Diseases.- Chapter 3. Pharmacogenomics of Antitumor Chemotherapeutic Agents.- Chapter 4. Pharmacogenomics of Antitumor Targeted Agent and Immunotherapy.- Chapter 5. Pharmacogenomics of Immunosuppressant.- Chapter 6. Pharmacogenomics of Psychiatric drugs.- Chapter 7. Pharmacogenomics of Anti-Infective Agents.- Chapter 8. Pharmacogenomics of Antithrombotic drugs.- Chapter 9. Pharmacogenomics in Therapeutic Drug Monitoring.- Chapter 10. Pharmacomicrobiomics.- Chapter 11. Genotyping technology in Pharmacogenomics.- Chapter 12. The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics.- Chapter 13. Cost-effectiveness of pharmacogenetic-guided treatment.- Chapter 14. Application of pharmacogenomics in drug discovery and development.- Chapter 15. Barriers and Solutions in Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine.