Main description:

Sjoegren's syndrome is a chronic autoimmune disease which can cause debilitating fatigue and pain. Diagnosis is often challenging due to the variability of symptoms and severity, and a multidisciplinary approach to management and treatment is required, yet there are few comprehensive resources covering everything clinicians need to know.

The Oxford Textbook of Sjoegren's Syndrome bridges this gap by offering extensive coverage of system by system manifestations and treatments, as well as practical, evidence-based advice on diagnosing and managing this condition. Bringing together recent advances in research and therapies, this up-to-date guide covers everything clinicians need to know from the fundamental science and clinical characteristics of this condition, to the immunological and biochemical aspects,
investigative procedures such as biopsy techniques and imaging modalities, and pharmacological and non-pharmacological interventions.

Contents:

Section 1: Introduction
1.1: Elizabeth J. Price and Anwar R. Tappuni: Introduction
1.2: Caroline Shiboski and Troy E. Daniels: Historical background, classification and diagnostic criteria
1.3: Simon Bowman: Epidemiology and genetics of Sjoegren s Syndrome
Section 2: Basic science
2.1: Onorina Berardicurti, Charlotte G. Smith, Roberto Giacomelli, Elizabeth J. Price, and Francesca Barone: Biomarkers in primary Sjoegren sSyndrome
2.2: Aurelie Ambrosi, Albin Bjoerk, and Marie Wahren-Herlenius: Autoantibodies and autoantigens in Sjoegren s Syndrome
2.3: Saba Nayar, Serena Colafrancesco, and Francesca Barone: Stromal cells in Sjoegren s Syndrome
Section 3: Diagnostic investigations
3.1: Anwar R. Tappuni: Clinical assessment of salivary glands function
3.2: Benjamin Fisher: Biopsy gland biopsy procedure and histopathology
3.3: Ashok Adams: Imaging in Sjoegren s Syndrome
Section 4: Head and neck manifestations and clinical management
4.1: Emily Carter: Salivary glands manifestations and management
4.2: Anwar R. Tappuni: Oral manifestations and management
4.3: Jennifer Fuller and Shakeel Shahdad: Dental related disease
Section 5: Ocular manifestations and management
5.1: Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo: Ocular Manifestations of Sjoegren s Syndrome
5.2: Nicola Roper, Pasquale Aragona, Maurizio Rolando, and Francisco C Figueiredo: A therapeutic strategy for Sjoegren s Syndrome dry eye
Section 6: Systemic manifestations
6.1: Thomas J Tull, Emma Benton, and David D Cruz: Cutaneous involvement and management of Sjoegren s Syndrome
6.2: Elizabeth J. Price: Musculoskeletal disease - presentation and management
6.3: Rhys Evans and Stephen Walsh: Renal involvement in Primary Sjoegren's Syndrome
6.4: Elizabeth J. Price: Gastrointestinal Disease in Sjoegren s syndrome
6.5: Aravind Ganesh, Shane Lyons, and Gabriel Yiin: Neurological complications of Sjoegren s Syndrome
6.6: Sara Carty: Cardiovascular and Lung Manifestations of Sjoegren s Syndrome
6.7: Coziana Ciurtin and Su-Ann Yeoh: Haematological Manifestations of Sjoegren s Syndrome
6.8: Coziana Ciurtin and Su-Ann Yeoh: Fatigue in Sjoegren s Syndrome
6.9: Katie Hackett and Helen Cartner: Non-pharmacological interventions for the management of Fatigue and Constitutional Symptoms in Sjoegren s Syndrome
6.1: Roberta Priori, Antonina Minniti, and Serena Colafrancesco: Gynaecologic and obstetric aspects in Sjoegren s Syndrome
6.11: Saad Rassam: Sjoegren s Syndrome Associated Lymphoma
Section 7: Juvenile and young adult
7.1: William D. Renton, Elizabeth J. Price, and A.V. Ramanan: Juvenile and young adult onset Sjoegren s Syndrome
Section 8: Sjogren s mimics and overlaps
8.1: Nurhan Sutcliffe: Mimics of Sjoegren s Syndrome
8.2: Nurhan Sutcliffe and Arabella Waller: Sjoegren s Syndrome overlaps
Section 9: Experimental treatments, emerging therapies and the future
9.1: Benjamin Fisher: Experimental therapies in primary Sjoegren s Syndrome
9.2: Elizabeth J. Price and Alan Baer: Sjoegren s Syndrome Summary of Clinical Management