This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system.
Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers' understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special "clinical correlates" sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.
History of Development of Gastrointestinal Physiology: From Antiquity to Modern Period and the Birth of Modern Digestive Physiology.- Structural and Functional Organization of Gastrointestinal Tract.- Cellular Organization of the GI Tract.- Intercellular Network of the GI Tract.- Molecular Basis of Regulation of GI Functioning.- Gastrointestinal Growth and Development: From Zygote to Adulthood.- Gastrointestinal Motor Function.- Gastrointestinal Hormones.- Neural Secretions and Regulation of Gut Functions.- Gut Immunomodulatory Functions.- Gastrointestinal Exocrine (Lumencrine) Secretions. The Reception Theory as the Basis for Developing the First Antisecretory Pharmacotherapy Drugs.- Chemical Digestion, Absorption and Transport.- Metabolic Functions of the Gut.- Excretory Functions of the GI Tract. Defecation.- Physiology of Helicobacter pylori.- Functional Relationship between the Gut and Other Organs of the Body.- Gastrointestinal Functioning in Extreme Conditions of Temperature, Pressure and Gravity.- Appendix.