Infertility affects an estimated 50 million women worldwide and has a wide range of causes including eating disorders, smoking, chemotherapy, diseases such as STIs, as well as genetic factors and malformations. The preliminary assessment and diagnosis involves a potentially broad array of lab and imaging tests, physical examination and potentially genetic tests, after which a management plan is selected depending on the woman’s age, the cause(s) and duration of the infertility.
Female Infertility: Core Principles and Clinical Management provides clinicians with a comprehensive understanding of how best to overcome infertility using the various treatment options now available.
The book opens with an introduction to the anatomy and physiology of the female reproductive system before describing the assessment and investigative tools used in primary and secondary healthcare settings. Subsequent chapters describe how to secure optimum functionality of the ovaries, the measurement of ovarian reserves, stimulation protocols and the process of oogenesis and oocyte collection. Given their potential adverse impact on the quality of oocytes and implantation, dedicated chapters focus on the treatment of polycystic ovarian syndrome and endometriosis.
Concluding chapters address fast moving and future technologies, including the use of pluripotent stem cells for treating different medical conditions; the management of mitochondrial disease and the transplantation of cryopreserved ovaries.
Highly illustrated and written by a team of international experts in the field, Female Infertility: Core Principles and Clinical Management serves as an essential resource for all clinicians, nurses and clinical scientists who specialise in reproductive medicine, gynecology, oncology, infertility and embryology.
CHAPTER 1 ANATOMY AND PHYSIOLOGY
CHAPTER 2 INVESTIGATION OF FEMALE INFERTILITY IN PRIMARY CARE
CHAPTER 3 INVESTIGATION OF FEMALE INFERTILITY IN SECONDARY CARE
CHAPTER 4 PRE-CONCEPTUAL CARE
CHAPTER 5 OVARIAN RESERVE AND ANTI-MULLERIAN HORMONE
CHAPTER 6 POLYCYSTIC OVARY SYNDROME
CHAPTER 7 ENDOMETRIOSIS
CHAPTER 8 DRUG INDUCED PROGRAMS
CHAPTER 9 ROLE OF OOCYTES IN IN VITRO FERTILISATION
CHAPTER 10: OOCYTE DONATION
CHAPTER 11 IMPLANTATION ISSUES
CHAPTER 12 SURROGACY
CHAPTER 13 SUPPORT AND COUNSELLING
CHAPTER 14 MANAGEMENT OF EARLY PREGNANCY
CHAPTER 15 MANAGEMENT OF GENETIC DISORDERS
CHAPTER 16 NON-INVASIVE PRENATAL TESTING
CHAPTER 17 DERIVATION OF OOCYTES FROM PLURIPOTENT STEM CELLS
CHAPTER 18 MITOCHONDRIAL DISEASE
CHAPTER 19 UTERINE TRANSPLANTATION
CHAPTER 20 FERTILITY PRESERVATION: OOCYTES