This book provides a comprehensive, state-of-the art review of current and new therapies in treating pancreatic cancer. In addition to discussing the current landscape for treating various stages of pancreatic cancer, the text highlights several standard and emerging approaches, with a particular emphasis on novel endoscopic, surgical, chemotherapeutic, radiotherapeutic, targeted, and immunotherapeutic strategies. The volume also features concepts on the potential economic effects associated with the development and implementation of new treatments in pancreatic cancer. Written by experts from a variety of integrative disciplines, Current and Emerging Therapies in Pancreatic Cancer is a valuable resource for oncologists, gastroenterologists, surgeons, and other professionals who treat and manage patients with pancreatic cancer.
Chapter 1 Pancreatic Cancer Epidemiology and Environmental Risk FactorsMahender Yellu, Chandana Kamireddy, Olugbenga O. OlowokureChapter 2 Anatomy of the Pancreas and Biliary TreeConstantinos P. Zambirinis, Peter J. AllenChapter 3 Pathology: Preneoplastic and Neoplastic Disease and Molecular GeneticsWei Chen, Ming Jin, Wendy L. FrankelChapter 4 Screening for Pancreatic Cancer: Who to Screen and How to Follow-up?Phil A. Hart, Peter P. Stanich, Heather HampelChapter 5 Staging and Prognostic ImplicationsAmit Mahipal, Richard KimChapter 6 Current and Emerging Therapies in Pancreatic CancerMaria Diab, Philip A. PhilipChapter 7 Imaging of Pancreatic MalignanciesFerenc Czeyda-Pommersheim, Bobby Kalb, Diego Martin Chapter 8 Advanced Endoscopic ProceduresJames J. FarrellChapter 9 How to Treat Resectable DiseaseMary Dillhoff, Mark BloomstonChapter 10 The Management of Locally Advanced Non-Metastatic Pancreas CancerBrent T. Xia, Young Kim, Syed A. AhmadChapter 11 Cytotoxic Therapy in Advanced Pancreatic Cancer: Where We Are and Where We Are HeadedNamrata Vijayvergia, Steven J. CohenChapter 12 Molecularly Targeted Therapies in Pancreatic CancerWalid Shaib, Bassel El-RayesChapter 13 Targeting the Tumor MicroenvironmentJulia Carnevale, Andrew H. KoChapter 14 Synthetic Lethality: Achilles Heel in Select Patient SubpopulationsMin Yuen Teo, Eileen M. O'ReillyChapter 15 Immune Therapies in Pancreatic CancerMohamad Bassam Sonbol, Mitesh J. BoradChapter 16 Vaccine Therapy in Pancreatic CancerBenjamin A. Weinberg, Michael J. PishvaianChapter 17 Virotherapies in Pancreatic CancerDaniel H. Ahn, Ramesh RamanathanChapter 18 Novel Radiotherapy ModalitiesLauren M. Rosati, Shalini Moning, Lauren Colbert, Sweet Ping Ng, Joseph M. Herman Chapter 19 The Role for Palliative Surgical Interventions in Pancreatic CancerAlexandra G. Lopez-Aguiar, Shishir K. MaithelChapter 20 Current and Emerging Therapies in Pancreatic Cancer: Do They Provide Value?Astrid Belalcazar, Olatunji B. Alese