Main description:

This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Contents:

Part I Principles of Clinical Molecular DiagnosticsChapter 1 Molecules of Diseases and Their Detection Methods

Chapter 2 Assay Performance Evaluation

Chapter 3 Establishment of Biological Reference Interval

Chapter 4 Ethics: Informed Consent, Patient Privacy

Chapter 5 Bioinformatics

Chapter 6 Report and Consultation

Chapter 7 Factors Associated with Variation

Chapter 8 Quality Control and Quality Assurance

Chapter 9 Precision Medicine

Part 2 Molecular Biomarkers and Signals from Diseased Functional Organ

Chapter 10 Molecules in Body Systems

Chapter 11 Molecules in Signal Pathways

Chapter 12 Endocrine and Metabolism

Chapter 13 Immune System

Chapter 14 Lipoproteins

Chapter 15 Transport and Carrier Proteins

Chapter 16 Coagulation and Fibrinolysis

Chapter 17 Cardiovascular System

Chapter 18 Pregnancy

Chapter 19 Urine

Chapter 20 Bone

Chapter 21 Cancer

Chapter 22 Translation Research of Novel Biomarker

Part 3 Advanced Molecular Diagnostic Techniques

Chapter 23 Next-generation Sequencing (NGS)

Chapter 24 Digital PCR

Chapter 25 Biosensor

Chapter 26 Microfluidic Chip

Chapter 27 Liquid Biopsy

Chapter 28 Molecular Targeted Imaging

Chapter 29 Fluorescence in Situ Hybridization

Chapter 30 Circulating DNA Quantification

Chapter 31 DNA Methylation Detection Techniques

Part 4 Disease Presentation and Clinical Laboratory Procedures

Chapter 32 Immunological Disorders

Chapter 33 Liver Diseases

Chapter 34 Pancreatic Diseases

Chapter 35 Digestive Tract Disease

Chapter 36 Kidney Diseases

Chapter 37 Cardiovascular Disease

Chapter 38 Lung Disease

Chapter 39 Blood Disorders

Chapter 40 Endocrine and Metabolic Diseases

Chapter 41 Neurological Disease

Chapter 42 Reproductive Organ Cancer

Chapter 43 Reproductive Organ Cancer

Chapter 44 Transplant Matching

Chapter 45 Paternity Test