Main description:

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair.

Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged.

The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Contents:

Imaging of Cell Grafts Past and Future of Cell based Heart Repair.- Progenitor Cells from the Adult Heart.- Epicardial Progenitors in the Embryonic and Adult Heart.- Cardiomyocyte Generation from human Pluripotent Stem Cells.- Derivation of Stroma Cells from human Pluripotent Stem Cells.- Direct Cardiac Programming.- Manufacturing of Therapeutic Cells.- Cardiac purification from iPSC-derived cell.- State-of-the-Art in Cardiomyocyte Transplantation.- State-of-the-Art in Tissue Engineering for Heart Repair.- Imaging of Cell Grafts.- Transplant Immunology.able.