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Vitamin D and the Lung
Mechanisms and Disease Associations
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Main description:

Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. The second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease. The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel.


Contents:

Section I - Introduction

1 Vitamin D Deficiency: Historical Perspectives

Kumaravel Rajakumar

Michael F. Holick

2 Perspective: Evolution of Human Skin Color: How Low Levels of Vitamin D Drove Natural Selection

Scott T. Weiss

Section II- Vitamin D Mechanisms of Relevance to Lung Diseases

3 Vitamin D and Lung Development in Early Life

Virender K. Rehan

John S. Torday

4 Vitamin D and the Innate Immune Response

Philip Liu

Aria Vazirnia

5 Vitamin D and Regulatory T Cells

Catherine Hawrylowicz

Zoe Urry

Sarah Dimeloe

6 Dendritic Cell Modulation by the Vitamin D System

Luciano Adorini

Gilles Laverny

Giuseppe Penna

7 Vitamin D Modulates Airway Smooth Muscle Function

Audreesh Banerjee

Reynold A. Panettieri, Jr.

8 Genetic and Genomic Effects

Kelan G. Tantisira

Section III. Disease Associations

9 Acute Respiratory Infections

Jonathan M. Mansbach

Carlos A. Camargo, Jr.

10 The role of vitamin D in the development, exacerbation, and severity of asthma and allergic diseases

Augusto A. Litonjua

11 Vitamin D and COPD

Wim Janssens

An Lehouck


PRODUCT DETAILS

ISBN-13: 9781627039628
Publisher: Springer (Humana Press Inc.)
Publication date: June, 2014
Pages: 332
Weight: 528g
Availability: Available
Subcategories: Diseases and Disorders, General Practice, Nutrition, Respiratory Medicine
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