Main description:

Adding to a vitally important cycle of publications covering the latest research developments in our understanding of neoplasms affecting the human central nervous system, this edition focuses on numerous aspects of pineal, pituitary, and spinal tumors. As with the previous volumes in the series, this latest work addresses a central imperative in cancer research-the need to standardize classifications, written definitions and investigative guidelines in order to achieve a measure of shared objectivity among academics engaged in one of the most important medical endeavors of our era. It brings together the very latest work by oncologists, neurosurgeons, physicians, research scientists, and pathologists, providing the medical community with a wealth of data and results that, taken together, will advance the cause of cancer research.

The volume synthesizes work on diagnosis, drug development, and therapeutic approaches that are typically scattered in a variety of journals and books. It features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery. Together with its counterpart publications, it represents a much-needed central resource that will inform and guide future research efforts.

Contents:

Preface
I. Pineal tumors
1. Papillary tumor of the pineal region
2. Pineal region tumors: clinical aspects
3. Papillary tumor of the pineal region: diagnosis
4. Pineal parenchymal tumors: immunohhistochemistry
5. Pineal parenchymal tumors: diagnostics and prognosis
6. Papillary tumors of the pineal region: diagnosis and treatment
7. Pineal region tumors: optimal neurosurgical treatment
II. Pituitary tumors
8. Pituitary tumors: genetics and heritable predisposition
9. Xanthogranulomas associated with pituitary adenomas: magnetic resonance imaging
10. Pituitary adenoma and craniopharyngioma: an overview
11. Familial pituitary adenomas: an overview
12. Papillary glioneuronal tumor
13. Solitary fibrous tumor
14. Pituitary adenomas: mcm2 protein as a cell proliferation marker
15. Pituitary adenomas: role of cyclin-dependent kinase inhibitors
16. Pituitary tumorigenesis: role of regulation of wee1 kinase by micrornas
17. Pituitary tumor cells: role of pkc , pkc , and pcke expression
18. Pituitary adenoma: role of hmga proteins
19. Pituitary adenomas: role of e-cadherin in tumor invasion
20. Pituitary tumorigenesis: role of the wnt signaling pathway
21. The role of aryl hydrocarbon receptor (ahr) and ahr-interacting
Protein (aip) in the pathogenesis of pituitary adenomas
22. Pituitary tumors: role of pituitary tumor- transforming gene-1
(pttg1)
23. Pituitary adenomas: endoscopic endonasal transphenoidal
Technique
24. Pituitary adenoma patients: hypofractionated cyberknife
Radiosurgery (method)
25. Transspheniodal/transcranial surgery of pituitary adenomas:
Prognosis-related occurrence for the trigemino-cardiac reflex
III. Spinal tumors
26. Spinal extradural meningiomas
27. Spinal cord ganglioglioma
28. Spinal angiolipoma: diagnosis and treatment
29. Spinal cord injury: tissue engineering using neural stem cells
30. Pediatric spinal tumors: total removal using laminotomy
31. Treatment of metastatic spinal epidural disease: surgery versus radiotherapy
32. Metastatic spinal cord compression from synovial sarcoma: surgical resection
33. Adult spinal intramedullary ependymomas: complete resection
34. Spinal intramedullary astrocytomas: prognostic factors
Index.