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The Neuregulin-I/ErbB Signaling System in Development and Disease
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Main description:

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. Neuregulin signals are also involved in the development diseases including breast cancer, heart disease and the pathogenesis of schizophrenia. This book reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.


Contents:

Introduction - Molecular control of development.- Biology of the Neuregulin/ErbB signaling network.- Neuregulins and their receptors.- Developmental functions of the Neuregulin-1/ErbB signalling pathway.- Interacting molecules - the Sox10/ErbB connection.- NRG-1/ErbB signals and disease.- Abbreviations.- References.- Subject index


PRODUCT DETAILS

ISBN-13: 9783540371052
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: March, 2007
Pages: 82
Weight: 145g
Availability: Available
Subcategories: General Issues, Neurology, Physiology
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