Advances in DNA sequencing and phylogenetic inference have created powerful methods to investigate many dangerous human viruses. The Molecular Epidemiology Of Viruses provides a comprehensive introduction to the use of genetic methods in molecular epidemiology and in-depth examples of analyses from many viruses.
Key topics included in this book are:
-Why genetic methods to track epidemiology are useful and how they can be used in disease control;
-The importance of sample design;
-DNA sequencing and other methods for genetic characterization;
- Genetic databases and their function as reference banks and information centers;
- How genetic analysis has been used to study the molecular epidemiology of both RNA and DNA viruses;
- How molecular techniques have been applied to monitor the spread of hepatitis viruses;
- In depth discussions of additional viruses including influenza, polio, human T-cell lymphotropic viruses, rabies, rotavirus, measles and respiratory syncytial virus, human papilloma virus, flavi viruses, hantaviruses, and potentially new and emerging human viruses.
This book is of interest to researchers in the fields of infectious disease, virology, microbiology, evolutionary biology, epidemiology and molecular biology as well as anyone interested in tracking the spread of disease.
Preface. Part One: Introduction to Molecular Epidemiology. 1. The Use of Molecular Epidemiology; T. Leitner. 2. DNA Technology for Molecular Analysis of Viruses; D. O'Meara, J. Lundeberg. 3. Phylogenetic Approaches to Molecular Epidemiology; K.A. Crandall, D. Posada. 4. The HIV Databases: History, Design and Function; B. Korber, C. Kuiken. Part Two: Application of Genetic Methods to Investigate Virus Spread. 5. The Evolution of Primate Lentiviruses and the Origins of AIDS; E. Bailes, R.R. Chaudhuri, M.L. Santiago, F. Bibollet-Ruche, B.H. Hahn, P.M. Sharp. 6. Recombination and Molecular Epidemiology of HIV-1 and Enteroviruses; M. Salminen. 7. Molecular Epidemiology of Human T Cell Leukemia/Lymphoma Viruses Type 1 and Type 2 (HTLV-1/2) and Related Simian Retroviruses (STLV-1, STLV-2 and STLV-L/3); A. Gessain, L. Meertens, R. Mahieux. 8. Molecular Epidemiology, Evolution and Dispersal of the Genus Flavivirus; P.M. de A. Zanotto, E.A. Gould. 9. Molecular Epidemiology of Hepatitis C Virus; A. Cochrane, P. Simmonds. 10. Seeking a Pale Horse: The 1918 Pandemic Influenza Virus; T.G. Fanning, A.H. Reid, T.A. Janczewski, J.K. Taubenberger. 11. Molecular Epidemiology in Measles Control; C.P. Muller, M.N. Mulders. 12. Public Health Surveillance and the Molecular Epidemiology of Rabies; J.E. Childs, J.W. Krebs, J.S. Smith. 13. Molecular Epidemiology of Rotavirus; C. Mittelholzer, L. Svensson. 14. Respiratory Syncytial Virus; P.A. Cane. 15. Molecular Epidemiology of Hantavirus Infections; Å. Lundkvist, A. Plyusnin. 16. Molecular Epidemiology of Arenaviruses; R.N. Charrel, X. de Lamballerie. 17. Molecular Epidemiology of Hepatitis B Virus; J.N. Zuckerman, A.J. Zuckerman. 18. Genomic Diversity of Human Papillomaviruses and its Impact on Molecular Epidemiological Research; H.-U. Bernard. Index.