Main description:

The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance.

Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications.

Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry.

Contents:

1. Anatomy of the spine
2. Biomechanics of the spine
3. Biomechanical models to study spinal phenotypes
4. Animal models to study spinal intervertebral disc phenotypes
5. Imaging technologies of the spine
6. Intervertebral disc degeneration
7. Disc space narrowing and osteophytes
8. Displacement of intervertebral discs
9. High-intensity zones and annular tears
10. Vertebral endplate abnormalities, defects, and changes
11. Vertebral bone marrow (Modic) changes
12. Ossification of the posterior longitudinal ligament
13. Lumbar spinal stenosis
14. Facet joints
15. Paraspinal muscles
16. Spinal alignment