Main description:

Sjoegren's Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjoegren's Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjoegren's Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist.
In addition to being a diagnostic guide, Sjoegren's Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjoegren's Syndrome patients and provides an exhaustive therapeutic update, focused on new agents and experimental techniques.
The inclusion of diagnostic/therapeutic algorithms illustrates the text with clinical photographs of the main organs involved and helps the reader to make guided diagnostic and therapeutic decisions through decision-based algorithms.

Contents:

Epidemiology.- Genetics and Proteomics.- Immunopathogenesis.- Viruses.- Etiopathogenic role of B-cells.- Oral involvement.- Ocular involvement.- Ear, nose and throat involvement.- Fatigue, fibromyalgia and other general symptoms.- Musculoskeletal involvement.- Non-vasculitic cutaneous involvement.- Vasculitis.- Cardiovascular involvement.- Pulmonary involvement.- Raynaud phenomenon.- Gastrointestinal involvement.- Autoimmune liver involvement.- Pancreatic involvement.- Nephro-urological involvement.- Central nervous system involvement.- Peripheral neuropathy.- Autonomic neuropathy.- Endocrine involvement.- Gynecological and obstetrical complications.- Laboratory abnormalities.- Diagnostic procedures (I).- Diagnostic procedures (II).- Immunological tests.- Classification criteria.- Measurement of chronicity and activity.- Measurement of quality of life.- Association with other autoimmune and rheumatic diseases.- Cancer.- Prognostic factors and survival.- SS in primary care.-Treatment of sicca features.- Treatment of B-cell lymphoma.- Classic immunosuppressive and immunomodulatory drugs.- New immunosuppressive and immunomodulatory drugs.- B-cell targeted therapies.- Other biological therapies.- Experimental therapies.