Main description:

This book casts new light on the field of oral drug absorption. It outlines both the concept of the past and the novel concept of Finite Absorption Time (FAT). In addition, the authors explore the correlated need for re-definition of bioavailability, bioequivalence providing a plethora of experimental data. Accordingly, this book is intended for academics/students or scientists working in pharmaceutical industries, regulatory agencies, and contract research organizations. It can be used for teaching purposes in under- and post-graduate courses dealing with biopharmaceutics, pharmacokinetics and biomedical engineering.

Contents:

Part I: Oral Pharmacokinetics.- Chapter 1. From Bateman (1908) To Dost (1953).- Chapter 2. The Unphysical Hypothesis Of Infinite Absorption Time.- Chapter 3. The Finite Absorption Time (Fat) Concept.- Chapter 4. The Rise Of Physiologically Based Finite Time Pharmacokinetic (Pbftpk) Models.- Part II: Bioavailability-Bioequivalence.- Chapter 5. History Of The Bioavailability-Bioequivalence Concepts.- Chapter 6. Therapeutic Equivalence Based On Bioequivalence Studies.- Chapter 7. Bioavailability Under The Prism Of Finite Absorption Time.- Chapter 8. Bioequivalence Under The Prism Of Finite Absorption Time.