(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
The role of the familial Alzheimer's Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.
Contents:
Molecular Genetics of the Presenilins in Alzheimer's Disease.- Alzheimer's Disease: A Matter of Dominance.- Alternative Endoproteolysis of the Presenilins and Familial Alzheimer's Disease.- The APP and PS1/2 Mutations Linked to Early Onset Familial Alzheimer's Disease Increase the Extracellular Concentration of A?1-42(43).- Metabolism and Function of Presenilin 1.- Mechanistic Studies of the Effect of Presenilins 1 and 2 on APP Metabolism.- Presenilin 2 - APP Interactions.- The Cellular Biology of Presenilin Proteins and a Novel Mechanism of Amyloid ?-Peptide Generation.- Regulation of Presenilin 1 Phosphorylation and Transcriptional Activation of Signal Transduction-Induced Genes by Muscarinic Receptors.- Neuronal Regulation of Presenilin-1 Processing.- Transgenic Approaches to the Study of Alzheimer's Disease.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: February, 2012
Pages: 116
Weight: 195g
Availability: Available
Subcategories: Neuroscience
From the same series
