Main description:

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine.

Contents:

1. Ethical Aspects of Precision Medicine: An Introduction to the Ethics and Concept of Clinical Innovation
2. Issues and Challenges in the Systematic Evaluation of Biomarker Tests
3. Statistical Learning in Precision Medicine
4. Biobanks as Basis of Individualized Medicine: Challenges Toward Harmonization
5. Sequencing in Precision Medicine
6. Workflow for Circulating miRNA Identification and Development in Cancer Research: Methodological Considerations
7. Analyzing the Effects of Genetic Variation in Noncoding Genomic Regions
8. Synthesis of Magnetic Iron Oxide Nanoparticles
9. Magnetic Particle Imaging
10. Nanoparticles and Nanosized Structures in Diagnostics and Therapy
11. Interaction of Nanoparticles With Biomolecules, Protein, Enzymes, and Its Applications
12. Modeling and Simulating Carcinogenesis
13. Sepsis: A Challenging Disease With New Promises for Personalized Medicine and Biomarker Discovery
14. Asphyxia Diagnosis: An Example of Translational Precision Medicine
15. Biomarker for Alzheimer's Disease