Main description:

This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain connectivity using PET and SPECT images, and the role of PET imaging in modulation of brain functioning by deep brain stimulation. The authors are renowned experts whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state of the art compendium will be invaluable for neurologists and radiologists/nuclear medicine specialists and will also be informative for interested general practitioners and geriatricians. Companion volumes on PET and SPECT in psychiatry and in neurobiological systems complete a trilogy.

Contents:

PART I: BASICS

1. Tracers for Neurology [Philip H. Elsinga, Groningen]

2. Tracer-Kinetic Modeling [Adriaan A. Lammertsma, Amsterdam]

3. Quantification in Brain SPECT: Noninvasive Cerebral Blood Flow Measurements [Hiroshi Matsuda, Tokyo]

4, Artificial Intelligence in the Analysis of PET scans of the Human Brain [Kim Mouridsen, Aarhus]

5. MRI/PET Imaging of the Brain [Michel Koole, Leuven]

6. The Default Network of the Brain [Koene R.A. van Dijk, Boston and Alexander Drzezga, Koeln]

7. Analysis of Brain Connectivity using PET, SPECT, and MRI [Carlos Sanchez, Ann Arbor]

PART II: DEMENTIA

8. Neuroimaging Findings in Dementia [Daniela Perani, Milano]

9. Abeta Imaging {Victor L. Villemagne, Melbourne]

10. Imaging of Tau Pathology [Victor L. Villemagne, Melbourne]

11. Nicotinic Acetylcholine Receptors [Osama Sabri, Leipzig]

12. Neuroimaging Findings in Mild Cognitive Impairment {Flavio M. Nobili, Genoa]

13. Impact of the IWG/Dubois Criteria for AD in Imaging Studies [Bruno Dubois, Paris]

14. Perfusion SPECT in the Diagnosis of AD [Gilles Stormezand, Groningen]

15. Nuclear Imaging in Frontotemporal Dementia [Fransje E Reesink, Groningen]

16. Parkinson Dementia: PET Findings [Nicolaas I. Bohnen, Ann Arbor]

17. SPECT/PET Findings in Lewy Body Dementia [Zuzanna Walker, London]

18. Vascular Dementia [Zhou Zhi, Beijing]

19. Value of MIBG in the Differential Diagnosis of Neurodegenerative Disorders [Mitsuhiro Yoshita, Toyama]

PART III: CEREBROVASCULAR DISORDERS

20. Perfusion Imaging in Healthy Human Ageing [Reinoud P.H. Bokkers, Groningen]

21. Carotid Plaque Imaging with SPECT/CT and PET/CT [Riemer H.J.A. Slart, Groningen]

22. PET in Brain Arteriovenous Malformations and Cerebral Proliferative Angiopathy [Marc van Dijk, Groningen]

23. PET Reveals Pathophysiology in Ischemic Stroke [W.Dieter Heiss, Koeln]

PART IV: MOVEMENT DISORDERS

24. Parkinson's Disease [A. Jon Stoessl, Vancouver]

25. Computer-Aided Diagnosis of Parkinson Disease, Based on SPECT Scans of the Dopamine Transporter

{Francisco Oliveira, Coimbra)

26. PET and SPECT Imaging in Parkinsonian Syndromes {David Eidelberg, Manhasset]

27. Amyotrophic Lateral Sclerosis [Martin R. Turner, Oxford]

28. PET in Huntington Disease [H.P.H. (Berry) Kremer, Groningen]

29. PET and SPECT Imaging in Dystonia [Marina A.J. de Koning-Tijssen, Groningen]

30. PET and SPECT Imaging in Hyperkinetic Movement Disorders [Marina A.J. de Koning-Tijssen, Groningen]

31. Clinical Applications of FP-CIT SPECT [Jan Booij, Amsterdam]

PART V: INFLAMMATORY DISORDERS

32. PET Imaging of Microglia Activation in Neuropsychiatric Disorders [Hans C. Klein, Groningen]

33. PET Imaging in Multiple Sclerosis [CWJ (Kars) van der Weijden, Groningen]

34. PET and SPECT Imaging of Neurotoxicity [Erik FJ de Vries, Groningen]

35. PET and SPECT in Hepatic and Uremic Encephalopathy [Georg Berding, Hannover]

PART VI: EPILEPSY

36. PET in Epilepsy [Matthias Koepp, London]

37. Neuroimaging of Epilepsy [William H Theodore and Sara Inati, Bethesda]

38. SISCOM: Subtraction Ictal SPECT Coregistered to MRI [Seung Bong Hong, Seoul]

PART VII: TUMORS OF THE NERVOUS SYSTEM

39. Gliomas [Karl Herholz, Manchester]

40. Neuro-SPECT of Brain Tumors [George A. Alexiou, Ioannina]

41. Methionine-PET to Distinguish Tumor Recurrence from Radionecrosis [Bart R.J.van Dijken, Groningen]

42. Brain Metastases of Neuroendocrine Tumors [Klaas P. Koopmans, Groningen]

OTHER SUBJECTS

43. Anesthesia and PET of the Brain (Anthony Absalom, Groningen]

44. Altered States of Consciousness: Coma, Sleep and Hypnosis [Aurore Thibaut, Liege]

45. Modulation of CNS Functions by Deep Brain Stimulation: Insights Provided by Molecular Imaging (Joseph

Tam, Toronto)

46. Imaging in Pediatric Neurology [Harry T Chugani, Detroit]