Main description:

Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as -sheet fibril-forming peptides and -helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.

Contents:

IntroductionBinding peptides for the functionalisation of nanomaterials in biomedicine Peptide-based biopolymers in biomedicine and biotechnology Cell penetrating peptides Bioactive peptides Nanostructured materials constructed from peptides Peptides for the synthesis of biomaterials and biomedical electronics Self-assembling peptides for tissue Peptide-based bioactive matrices for regenerative medicineAntimicrobial peptides Peptides and drug delivery Peptide-target interaction modelling