Main description:

In this issue of Surgical Pathology Clinics, guest editor Dr. Aatur D. Singhi brings his considerable expertise to the topic of Pancreatobiliary Neoplastic Pathology. Top experts in the field discuss precursor and malignant neoplasms (with mimics) such as molecular discoveries (e.g., IOPNs), neoadjuvant treatment histopathology (e.g., grading), immunohistochemical biomarkers (e.g., prognostic markers for neuroendocrine tumors), and more.

Contains 13 relevant, practice-oriented topics including the diagnostic challenge of evaluating small biopsies from the pancreatobiliary system; integrating molecular analysis to the pathologic evaluation of pancreatic cysts; the cytomorphologic and molecular assessment of bile duct brushing specimens; advances in the surgical approach to pancreatobiliary neoplasms; and more.

Provides in-depth clinical reviews on pancreatobiliary neoplastic pathology, offering actionable insights for clinical practice.

Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Contents:

The Diagnostic Challenge of Evaluating Small Biopsies from the Pancreatobiliary System
Integrating Molecular Analysis into the Pathologic Evaluation of Pancreatic Cysts
The Cytomorphologic and Molecular Assessment of Bile Duct Brushing Specimens
Advances in the Surgical Treatment of Pancreatic Cancer
The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice
Total Pancreatectomy with Islet Autotransplantation: New Insights on the Pathology and Pathogenesis of Chronic Pancreatitis from Tissue Research
The Histopathology of Neoadjuvant-Treated (NAT) Pancreatic Ductal Adenocarcinoma
The Molecular Pathogenesis and Targeted Therapies for Cholangiocarcinoma
Prognostic and Predictive Biomarkers for Pancreatic Neuroendocrine Tumors
Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms of the Pancreas
The Clinical and Pathologic Features of Intracholecystic Papillary-Tubular Neoplasms of the Gallbladder