Main description:

This detailed, practical textbook focuses on immune mediated disorders of the nervous system with particular focus on systemic autoimmune disorders. Divided into three sections, the first discusses the neuroanatomical and pathophysiologic basis of immune mediated disorders of the nervous system. Following this are 25 chapters devoted to individual clinical conditions. To conclude, the final section explains what is known about the mechanisms of immunomodulatory treatments and practical points about monitoring patients on these treatments.

Neurorheumatology: A Comprehensive Guide to Immune Mediated Disorders of the Nervous System bridges the gaps among different branches of medicine and is an indispensable resource for rheumatologists and neurologists looking to develop a firm understanding of these dynamic disorders

Contents:

I. Physiology and Testing

The central and peripheral nervous system

Inflammation in the nervous system

Signs and symptoms of relevant rheumatological disorders

Imaging

Laboratory testing

Electrophysiological studies

Biopsy

II. Diseases and their Nervous System Effects

Systemic Lupus Erythematosus

Antiphospholipid and thrombotic microangiopathies

Sjoegren Syndrome

Rheumatoid Arthritis

Sarcoidosis

Seronegative spondyloarthropathy

IgG4-Related Disease

Scleroderma

Giant Cell Arteritis

CNS vasculitis

Neuro-Beh et Disease

Autoinflammatory Diseases

Ocular + Auditory Inflammatory Syndromes

Paraneoplastic Syndromes

Neuronal Surface Antibody-Mediated Autoimmune Encephalitis

Hashimoto's encephalopathy/SREAT

Celiac Disease

Neuromyelitis Optica

Multiple sclerosis and relation to systemic autoimmune disorders

Stiff-person Syndrome

Inflammatory myopathies

Neuromuscular Junction Disorders

Peripheral neuropathy in rheumatologic disorders, plexopathy

Chronic Fatigue Syndrome/Systemic Exertion Intolerance Disease

Lyme Disease

Complications related to pharmacotherapy

Amyloidosis

III. Guide to Rheumatological Diagnosis and Tests by Syndrome -

Clinical syndrome tables

Differential diagnoses

IV. Overview of immunomodulatory treatment paradigms

Corticosteroids

Oral steroid-sparing agents

Cyclophosphamide

Biologics

IVIG

Plasmapheresis