Main description:

This book reviews the role of the lung microbiome in the development and progression of lung diseases. It deals with the role of microbiota dysbiosis in influencing host defense and immunity leading to resistance, colonization, and disease exacerbation. The book delineates the complex interaction between pathogen and lung residual microbiota during disease conditions. It further highlights the potential role of lung microbiota as the key modulator of lung carcinogenesis and immune response against cancer cells. Lastly, it reviews technological developments for unraveling the lung microbiome that profoundly impacts clinical diagnostics. This book is an essential resource for the scientists working in pulmonary diseases, pharmaceutical & clinical sciences, and pulmonary clinicians.

Contents:

Introduction to Lung Diseases.- Introduction to Microbiome.- Role of Microbiome in Inflammation.- The interplay of microbiome, inflammation, and immunity in inflammatory lung diseases.- Microbiome in Asthma.- Microbiome in Chronic Obstructive Pulmonary Disease.- Microbiome in Asthma-COPD Overlap syndrome (ACO).- Microbiome in ARDS (Acute Respiratory Distress Syndrome).- Role of brain-gut- microbiome axis in Depression co-morbid with COPD or Asthma.- Microbiome in Lung Cancer.- Microbiome in Pulmonary Tuberculosis.- Lung Microbiome: Friend or Foe of Mycobacterium tuberculosis.- Microbiome in Idiopathic Pulmonary Fibrosis. Microbiome in SARS-Cov2 (Covid-19).- Status of the microbiome in SARS-Cov2 (Covid-19).- Microbiome in Influenza-A Virus Infection.- Microbiome in Upper Respiratory Tract Infection (URTI).- Challenges in understanding the lung microbiota.- Microbiome in Inflammatory Lung Diseases: Challenges and Future Prospects.- Microbiota targeted via nanotechnology for lung cancer therapy: Challenges and future perspectives.