Main description:

This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics.

The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.

Contents:

Chapter 1_Exploring the Potential of Microbial Engineering: The Prospect, Promise and Essence. -Chapter 2_Role of Systems Biology in Microbial Engineering. -Chapter 3_Synthetic Biology: Refining Human Health. -Chapter 4_Probiotic Engineering: A focus on Inflammatory Bowel Disease. -Chapter 5_Engineering microbes for smart diagnostics & Lab on Chip. -Chapter 6_Bacteriophage and Virus Engineering. -Chapter 7_CRISPR Technologies: A tool for Engineering Microbes. -Chapter 8_Recombinant Vaccines: The Revolution Ahead. -Chapter 9_ Microbe-Host Metabolic Interaction: Probiotic Approach. -Chapter 10_Health Solutions with Synthetic Biology. -Chapter 11_Designer Microbes: Oncotherapy approach . -Chapter 12_Engineering human Microbiome: Promise for treating disease. -Chapter 13_Use of Engineered Bacteria for Production of Green Chemicals & Pharmaceuticals. -Chapter 14_Fat Fighting Microbes. -Chapter 15_Scale-up of engineering strain for industrial applications. -Chapter 16_Affordable Product Innovation through Engineered Microbes. -Chapter 17_ COVID-19: Lesson Learnt from Diagnostics to therapeutics