Main description:

This book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications.

After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of stem cells particularly in relation to MSCs. In turn, it reviews materials and methods used to isolate MSCs from various sources, culture expansion, characterization and long-term storage. It also explores the therapeutic efficacy, immunomodulation and anti-inflammatory, and differentiation properties of MSCs.

Importantly, the book discusses the applications of genetic engineering to enhance the efficacy and potential of MSCs in regenerative medicine. The book largely addresses the potential applications of mesenchymal stem cells in therapies for important species of domesticated animals including sheep, goats, cattle, buffalo, cats, dogs and horses. Finally, the book presents an abridgement of challenges and future prospects of stem cell research and application in medicine, in general and veterinary sciences, in particular.

Contents:

Chapter1_Stem cell developmental history. -Chapter 2_Stem cell and its properties. Chapter 3_Mesenchymal stem cell isolation, culture, characterization and cryopreservation. -Chapter 4_Mesenchymal stem cell immuno-modulation and/ anti-inflammatory properties. -Chapter 5_Mesenchymal stem cell properties and available micro-environment. -Chapter 6_ Mesenchymal stem cell genetic engineering and regenerative medicine. -Chapter 7_Sheep mesenchymal stem cell basic research and potential applications. -Chapter 8 Goat mesenchymal stem cell basic research and potential applications. -Chapter 9_Cattle/buffalo mesenchymal stem cell basic research and potential applications. -Chapter 10_Cat mesenchymal stem cell characteristics and potential applications. -Chapter 11_Dog mesenchymal stem cell basic research and potential applications. -Chapter 12_Equine mesenchymal stem cell basic research and potential applications. -Chapter 13_The future of mesenchymal stem cell research.