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Medicinal Chemistry of Anticancer Drugs
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Main description:

Medicinal Chemistry of Anticancer Drugs, Third Edition provides an updated resource for students and researchers from the point-of-view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. The new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer.

Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point-of-view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references, reviews and primary literature.


1. Introduction
2. Antimetabolites
3. Anticancer Drugs That Modulate Hormone Action
4. Anticancer strategies involving radical species
5. DNA Alkylating Agents
6. Anticancer Drugs That Interact with the DNA Minor Groove
7. Anticancer Drugs acting by DNA intercalation and topoisomerase inhibition
8. Epigenetic Therapy of Cancer
9. Anticancer Drugs Targeting Tubulin and Microtubules
10. Drugs Tacting on signaling pathways, part 1: Tirosine kinase inhibitors
11. Anticancer drugs acting on signaling pathways, part 2
12. Protein degradation-based cancer therapy
13. Cancer immunotherapy
14. Miscellaneous small-molecule and biological approaches to cancer therapy
15. Drug Targeting in Anticancer Chemotherapy
16. Drugs That Modulate Resistance to Anticancer Agents
17. Cancer Chemoprevention


ISBN-13: 9780128185490
Publisher: Elsevier (Elsevier Science Publishing Co Inc)
Publication date: June, 2022
Pages: 926
Weight: 610g
Availability: Contact supplier
Subcategories: Biochemistry, Pharmacology
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