Main description:

This definitive text on respiratory disease in children has been completely updated and revised for the 7th Edition. Several new chapters have been added, including information on the impact of environmental pollution on lung disease in children. Provides the most authoritative and comprehensive coverage available of basic science and clinical problems related to pediatric lung disease.

Contents:

Section I General Basic Considerations

1 Molecular Determinants of Lung Morphogenesis

2 Basic Genetic and Epigenetics of Childhood Lung Disease

3 Gene by Environment Interaction in Respiratory Diseases

4 The Surfactant System

5 The Structural and Physiologic Basis of Respiratory Disease

6 Biology and Assessment of Airway Inflammation

7 Lung Defenses: Intrinsic, Innate, and Adaptive

8 The History and Physical Examination

9 Bronchoscopy and Bronchoalveolar Lavage in Pediatric Patients

10 Diagnostic Imaging of the Respiratory Tract

11 Pulmonary Function Tests in Infants and Preschool Children

12 Pulmonary Function Testing in Children

13 Exercise and Lung Function in Child Health and Disease

14 Integrating Patient-Reported Outcomes into Research and Clinical Practice

15 Children Dependent on Respiratory Technology

16 Transition from Pediatric to Adult Care

17 Long-Term Consequences of Childhood Respiratory Disease

18 Drug Administration by Inhalation in Children

19 Physical Therapies in Pediatric Respiratory Disease

20 Modern Molecular Therapies for Respiratory Disease

21 Congenital Lung Disease

22 Respiratory Disorders in the Newborn

23 Bronchopulmonary Dysplasia

24 Microbiologic Diagnosis of Respiratory Illness: Practical Applications

25 Acute Infections That Produce Upper Airway Obstruction

26 Bronchitis

27 Bronchiolitis

28 Viral Pneumonia

29 Community-Acquired Bacterial Pneumonia

30 Bronchiectasis and Chronic Suppurative Lung Disease

31 Influenza

32 Atypical Pneumonias in Children

33 Tuberculosis and Nontuberculosis Mycobacterial Disease

34 The Mycoses

35 Pertussis and Other Bordetella Infections of the Respiratory Tract

36 Toxocariasis, Hydatid Disease of the Lung, Strongyloidiasis, and Pulmonary Paragonimiasis

37 Atelectasis

38 Pulmonary Edema

39 Acute Respiratory Distress Syndrome

40 Lung Injury from Hydrocarbon Aspiration and Smoke Inhalation

41 Drowning

42 Tumors of the Chest

43 Chest Wall Function and Respiratory Muscle Disorders

44 The Epidemiology of Asthma

45 The Immunopathogenesis of Asthma

46 Asthma in the Preschool-Age Child

47 Wheezing in Older Children: Asthma

48 Severe Asthma

49 The Influence of Upper Airway Disease on the Lower Airway

50 Genetics and Pathophysiology of Cystic Fibrosis

51 Diagnosis and Presentation of Cystic Fibrosis

52 Pulmonary Disease in Cystic Fibrosis

53 Nonpulmonary Manifestations of Cystic Fibrosis

54 New Concepts in Children's Interstitial Lung Disease and Diffuse Lung Disease

55 Childhood Interstitial Lung Disease Disorders More Prevalent in Infancy

56 Lung Diseases Associated with Disruption of Pulmonary Surfactant Homeostasis

57 Pulmonary Involvement in the Systemic Inflammatory Diseases of Childhood

58 Diffuse Alveolar Hemorrhage in Children

59 Environmental Exposures in the Normal Host

60 Rare Childhood Lung Disorders

61 Primary Immunodeficiency: Chronic Granulomatous Disease and Common Variable Immunodeficiency Disorders

62 Pulmonary Disease in the Pediatric Patient with Acquired Immunodeficiency States

63 Respiratory Disorders in Pediatric HIV Infection

64 Pediatric Lung Transplantation

65 The Aerodigestive Model

66 Aspiration

67 Feeding, Swallowing, and Voice Disorders

68 Gastroesophageal Reflux Disease and Eosinophilic Esophagitis in Children with Complex Airway Disease

69 Laryngeal and Tracheal Airway Disorders

70 Air and Liquid in the Pleural Space

71 Primary Ciliary Dyskinesia

72 Childhood Pulmonary Arterial Hypertension

73 The Lung in Sickle Cell Disease

74 Lung Injury Caused by Pharmacologic Agents

75 Disorders of the Respiratory Tract Caused by Trauma

76 Sudden Infant Death Syndrome and Apparent Life-Threatening Events

77 Disorders of Breathing During Sleep