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Innate and Adaptive Immunity in the Tumor Microenvironment
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Main description:

Traditionally, the interplay between cancer cells and host immunity has been studied systemically. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. This volume compiles reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease.


Contents:

Foreword - Tumor Microenvironment under the Magnifying Glass: A New Challenge to Cancer Immunologists
Eitan Yefenof Chapter 1: Immune Effector Cells in the Tumor Microenvironment: Their Role in Regulation of Tumor Progression
Theresa L. Whiteside Chapter 2: Histocompatibility Antigens, Tumor Microenvironment and Escape Mechanisms Utilized by Tumor Cells
Soldano Ferrone and Theresa L. Whiteside Chapter 3: Local Tumor Growth and Spontaneous Systemic T cell Responses in Cancer Patients: a Parodox and Puzzle
Philipp Beckhove and Volker Shirrmacher Chapter 4: Insights into mechanisms of immune resistance in the tumor microenvironment through molecular profiling
Thomas F. Gajewski Chapter 5: Tumor Antigens as Modulators of the Tumor Microenvironment
Katja Engelmann and Olivera J. Finn Chapter 6: Tumor Cell Resistance to Apoptosis by Infiltrating Cytotoxic Lymphocytes
Benjamin Bonavida Chapter 7: The Tumor Microenvironment as a Model for Tissue-Specific Rejection
Silvia Selleri, Sara Deola, Cristiano Rumio and Francesco M. Marincola Chapter 8: Functional Cytotoxicity of T Cells at the Tumor Environment
Michal Lotem, Arthur Machlenkin, Shoshana Frankenburg and Tamar Peretz Chapter 9: Natural Killer Cells at the Tumors Microenvironment
Roi Gazit and Ofer Mandelboim Chapter 10: Contribution of the Microenvironment to the Pathogenesis of EBV-positive Hodgkin and NK/T-cell Lymphomas
Eva Klein, M. Takahara and LL Kis


PRODUCT DETAILS

ISBN-13: 9781402067495
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: December, 2007
Pages: 224
Weight: 512g
Availability: Available
Subcategories: General Issues, Immunology, Oncology
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