Main description:

Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more.

Contents:

1. Molecular and tissue basis of inflammation in health and disease (Marion Tible, Thomas Tourdias)

Imaging Approaches to Inflammation

2. Sensitivity and specificity of diffusion MRI to neuroinflammatory processes (Ileana O. Jelescu, Els Fieremans)

3. Iron imaging in neuroinflammation (Vanessa Wiggermann)

4. MRS in neuroinflammation (Ashley D. Harris, Erin L. MacMillan)

5. Magnetization transfer and chemical exchange saturation transfer in neuroinflammation (Seth A. Smith, Kristin P. O'Grady, Anna J.E. Combes, Colin McKnight, Francesca R. Bagnato)

6. Gadolinium based imaging of the blood brain barrier and of the brain waste clearance pathways (Nivedita Agarwal, Daniel M. Harrison)

7. Magnetic particle imaging (Natasha N. Knier, Olivia C. Sehl, Julia J. Gevaert, Ashley V. Makela, Paula J. Foster)

8. Positron Emission Tomography Tracers for Detecting Inflammation (Shalini Sharma, Mukesh K. Pandey)

Animal Models

9. The use of animal models of neuroinflammation for imaging studies (Jeff Dunn, Qandeel Shafqat)

Human inflammation-based diseases

10. Stroke (Jennifer K. Ferris, Lucero Aceves-Serrano, Justin W. Andrushko, Lara A. Boyd)

11. Central Nervous System Vasculitis (Wenjie Yang, Bruce A. Wasserman)

12. Dementia (Maura Malpetti, James B Rowe, Li Su, John T O'Brien)

13. Parkinson's Disease (Shu-Ying Liu, Vesna Sossi)

14. Amyotrophic lateral sclerosis (Sicong Tu, Matthew Kiernan)

15. Multiple sclerosis (Nara Miriam Michaelson, Neha Vijayvargiya Safi, Ulrike W. Kaunzner, Susan A. Gauthier)

16. Pediatric Leukodystrophies (Deborah L. Renaud)

17. Lupus (Theodor Rumetshofer, Efrosini Papadaki, Andreas Joensen, Pia C. Sundgren)

18. Autoimmune Encephalitis (Vyanka Redenbaugh, Eoin P. Flanagan)

19. Neuroinflammation and schizophrenia spectrum disorders (S. Andrea Wijtenburg, Laura M. Rowland)