Main description:

Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more.

Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).

Contents:

Preface

Max Costa

1. Mechanisms of chromate carcinogenesis by chromatin alterations

Hesbon A. Zablon, Andrew VonHandorf and Alvaro Puga

2. Chemical mechanisms of DNA damage by carcinogenic chromium(VI)

Casey Krawic and Anatoly Zhitkovich

3. The dark side of NRF2 in arsenic carcinogenesis

Matthew Dodson, Jinjing Chen, Aryatara Shakya, Annadurai Anandhan and Donna D. Zhang

4. Breast carcinogenesis induced by organophosphorous pesticides

Gloria M. Calaf

5. Tungsten toxicity and carcinogenesis

Alicia M. Bolt

6. Arsenic and cancer: Evidence and mechanisms

Rachel M. Speer, Xixi Zhou, Lindsay B. Volk, Ke Jian Liu and Laurie G. Hudson

7. miRNAs and arsenic-induced carcinogenesis

Alexandra N. Nail, Ana P. Ferragut Cardoso, Lakyn K. Montero and J. Christopher States

8. Epigenetic and epitranscriptomic mechanisms of chromium carcinogenesis

Zhishan Wang and Chengfeng Yang

9. Polyadenylation of canonical histone H3.1 in carcinogenesis

Arul Veerappan, Aikaterini Stavrou and Max Costa

10. Genetic and environmental reprogramming of the sarcoma epigenome

Anne Grand'Maison, Rachael Kohrn, Emmanuel Omole, Mahek Shah, Peter Fiorica, Jennie Sims and Joyce E. Ohm

11. Epigenomic reprogramming in iAs-mediated carcinogenesis

Smitha George, Richard N. Cassidy, Wesley N. Saintilnord and Yvonne Fondufe-Mittendorf