Main description:

Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington's disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington's Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more.

Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson's and Huntington's disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovations in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease.

Contents:

1. Challenges in translating a cell therapy to GMP Gerhard Bauer 2. The challenges in developing a cell therapy for Huntington's disease. Anne Rosser 3. Challenges of cell therapies for retinal diseases Christell Monville 4. Challenges of gene therapy in Huntington's Disease 5. Technological advances and barriers to gene therapy 6. Considerations in the development of cell therapy modulation for spinal cord injury treatment Michael Aron Lane 7. Challenges of developing glial cell therapy for ALS Michal Izrael 8. Exploring cell and gene therapy in current animal models of Parkinson's and Huntington's disease Mariah J. Lelos 9. Considerations for the use of biomaterials to support cell therapy in degenerative disease James Benjamin Phillips 10. Neurosurgical challenges/innovations in cell and gene therapy delivery William Gray 11. Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders 12. Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease Cheney Drew and Monica Busse 13. More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease Emma Lane