Main description:

Gap-junction proteins, connexins are important cellular entities that regulate various facets of cellular physiology. The connexins constitute large family of proteins. The present book provides basic overview about various aspects of connexin proteins. The book has tried to touch the fundamental aspects of connexin family. This book will be useful to broad audience that includes under-and post-graduate students, research scholars, clinicians, etc. The reference section at the end of the book will be helpful for those who seek to know deeper details about this family of proteins.

Feature:

The book compiles the scattered information on connexions in one volume

The book addresses the specific needs of the scientific community by bringing latest and up-to-date information on connexins

This cutting-edge work will be informative to scientists wishing to learn about the field, as well as to those who are active researchers in this area

The complex concepts have been explained in a reader-friendly manner

Back cover:

Gap-junction proteins, connexins are important cellular entities that regulate various facets of cellular physiology. The connexins constitute large family of proteins.  The present book provides basic overview about various aspects of connexin proteins. The book has tried to touch the fundamental aspects of connexin family. This book will be useful to broad audience that includes under-and post-graduate students, research scholars, clinicians, etc. The reference section at the end of the book will be helpful for those who seek to know deeper details about this family of proteins.

Contents:

1. Introduction.- 2. Historical and Topological Perspective of Connexins.- 3. Molecular Components and Nomenclature of Gap Junctions.- 4. General Cell Biology of Connexins.- 5. Genomic Organization of Connexins.- 6. Transcriptional Regulation of the Connexin Gene.- 7. Epigenetic Regulation of Connexins.- 8. Translation Regulation of Connexins.- 9. Interaction Partners of Connexin Proteins.- 10. Tissue Distribution of Connexins.- 11. Connexin Functions.- 12. Connexin Mutations and Disease.- 13. Suggested Reading.