(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
The hematopoietic system plays roles that are crucial for survival of the host: delivery of oxygen to tissues, arrest of accidental blood leaking from blood vessels, and fending off of invading microbes by humoral, cell-mediated, and phagocytic immunity. The activity of the hematopoietic system is staggering: daily, a normal adult produces approximately 2.5 billion erythrocytes, 2.5 billion platelets, and 1 billion granulocytes per kilogram of body weight. This production is adjusted in a timely fashion to changes in actual needs and can vary from nearly none to many times the normal rate depending on needs which vary from day to day, or even minute to minute. In response to a variety of stimuli, the cellular components of the blood are promptly increased or decreased in production to maintain appropriate numbers to optimally protect the host from hypoxia, infection, and hemorrhage. How does this all happen and happen without over or under responding? There has been extraordinary growth in our understanding ofhematopoiesis over the last two decades. Occupying center stage is the pluripotent stern cell and its progeny. Hematopoietic stern cells have been characterized by their capacity for self renewal and their ability to proliferate and differentiate along multiple lineages. Few in number, the stern cell gives rise to all circulating neutrophils, erythrocytes, lymphoid cells, and platelets. In hematopoietic transplantation, the stern cell is capable of restoring long-term hematopoiesis in a lethally irradiated host.
Contents:
List of Contributors. Introduction. I. Biology of Hematopoietic and Lymphopoietic Cytokines. II. Management of Neutropenia and Neutropenic Fever. III. Management of Anemia. IV. Management of Thrombocytopenia. V. The Role of Cytokines to Enhance Cancer Chemotherapy. VI. Management of Marrow Failure States. VII. The Use of Cytokines in Blood and Marrow Transplantation. Index.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: October, 2012
Pages: 419
Weight: 640g
Availability: Available
Subcategories: Haematology, Oncology
From the same series
Dirk J. Ruiter
R. Verley
H.F. Seigler
Kenneth V. Honn
Franco M. Muggia
P. Hilgard
Noburo Kobayashi
James M. Church
L. Dogliotti
A. Giacosa
Seymour Garte
John Masters
Kintomo Takakura
B.A. Stoll
J. Mark Elwood
Laurence H. Baker
Laurence H. Baker
B.A. Stoll
A. Giacosa
Franco M. Muggia
Matthew J. van Zwieten
L.A. Liotta
Kenneth A. Foon
P.I. Reed
Paul H. Sugarbaker
Gabriel A. Kune
Frederick A. Valeriote
R. Ceriani
B. Lowenberg
D.G. Poplack
J. Bánóczy
Thomas R. Tritton
Miles P. Hacker
Aaron Polliack
B. Lowenberg
Pelayo Correa
Alexander H.G. Paterson
Franco M. Muggia
J. Aisner
Stephen T. Sonis
F.J. Cleton
Kenneth V. Honn
Stephen T. Sonis
Soldano Ferrone
Stephen B Howell
C.C. Tijssen
B.W. Hancock
B.W. Ongerboer de Visser
A.P.M. Heintz
B.A. Stoll
A.M. Ward
Daniel L. Kisner
Marvin A. Rich
J. Gordon McVie
J.R. Ryan
Marvin A. Rich
Kenneth V. Honn
D.G. Poplack
Anthony J. Mastromarino
Frederick A. Valeriote
Marvin A. Rich
Laurence H. Baker
P.K. Pattengale
G.B. Snow
Frederick A. Valeriote