Published August, 2011
By Rudolf Valenta and Robert L. Coffman
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

In fact, more than 25% of the population suffer from IgE-mediated allergies which therefore represent a major health burden of our society, particularly because untreated allergy often progresses to severe disabling forms of disease, such as asthma and sometimes kills sensitized people through anaphylaxis.

---

Published May, 2011
By Michael Karin
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

---

Published April, 2011
By Glenn Dranoff
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells.

---

Published April, 2011
By Rafi Ahmed and Tasuku Honjo
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue.

---

Published March, 2011
By Inger Helene Madshus
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

---

Published January, 2011
By Lyubomir T. Vassilev, David Fry and Lyubomir Vassilev
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions.

---

Published December, 2010
By Martin L. Privalsky
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators.

---

Published December, 2010
By Walter Doerfler, Petra Bohm and Petra Boehm
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. After the first volume on virion and structure, viral replication and host-cell interaction this second volume deals with the immune system, oncogenesis and gene therapy.

---

Published December, 2010
By Georg Gosztonyi
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

It has been recognized that viruses can induce neuronal damage by a variety of mechanisms. The specific mechanisms of damage involved in retroviral infections and in prion diseases of the nervous system are reviewed, and finally how autoimmune diseases can lead to neuronal damage.

---

Published December, 2010
By Alexander Steinkasserer
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Dendritic cells are vital to induce potent anti-viral immune responses. On the one hand they are able to mount potent antiviral immune responses, and on the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes where they infect their prime target.

---