Main description:

Originally published in 2006, this is a comprehensive and definitive account of the human male gamete. The volume summarizes many unique and revealing characteristics of the sperm cell. It provides a detailed overview of human sperm production, maturation and function, and looks at how these processes affect and influence fertility, infertility and ART. The volume thus provides a detailed review of the most important research and developments, augmented with pertinent references. This book will appeal to all practitioners and scientists in reproductive medicine and in particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.

Contents:

1. Anatomical and compartmental analysis Peter Sutovsky and Gaurishankar Manandhar; 2. Sperm chromatin stability and susceptibility to damage in relation to its structure Jeffrey A. Shaman and W. Steven Ward; 3. Genomic and proteomic approaches to defining sperm production and function Sarah Conner, Linda Lefièvre and Christopher L. R. Barratt; 4. The epididymis and sperm maturation Trevor Cooper and C. H. Yeung; 5. Control of motility Claude Gagnon and Eve de Lamirande; 6. Regulation of capacitation Pablo Visconti and B. M. Gadella; 7. ROS's: friend or foe John Aitken and Liga Bennetts; 8. Testing sperm manufacturing quality: the sperm-zona binding assay Sergio Oehninger and Daniel Franken; 9. Genetics: a basic science perspective Peter Vogt; 10. Sex chromosome abnormalities and male infertility: a clinical perspective Shai Shefi and Paul J. Turek; 11. Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome Jacquetta Trasler and Sophie La Salle; 12. The DAZ gene family and human germ cell development from embryonic stem cells Mark S. Fox, Renee A. Reijo Pera and Amander T. Clark; Index.