Main description:

Since 1977, this outstanding book has been the immunology reference of choice for both veterinary students and practitioners. It's the only complete resource on the subject, featuring a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts.

Contents:

1. The Defense of the Body
2. Innate Immunity: The Recognition of Invaders
3. Innate Immunity: Proinflammatory and Antimicrobial Mediators
4. Innate Immunity: Neutrophils and Phagocytosis
5. Innate Immunity: Macrophages and Recovery from Inflammation
6. Systemic Responses to Inflammation
7. Innate Immunity: The Complement System
8. Cell Signaling: Cytokines and Their Receptors
9. Antigens: Triggers of Adaptive Immunity
10. Dendritic Cells and Antigen Processing
11. The Major Histocompatibility Complex
12. Organs of the Immune System
13. Lymphocytes
14. Helper T Cells and Their Response to Antigen
15. B Cells and Their Response to Antigen
16. Antibodies: Soluble Antigen Receptors
17. How Antigen-Binding Receptors are made
18. T-Cell Function and the Destruction of Cell-Associated Invaders
19. The Third Lymphocyte Population: Natural Killer Cells
20. Regulation of Adaptive Immunity
21. Immunity in the Fetus and Newborn
22. Immunity at Body Surfaces
23. Vaccines and Their Production
24. The Use of Vaccines
25. Immunity to Bacteria and Fungi
26. Immunity to Viruses
27. Immunity to Parasites
28. Type I Hypersensitivity
29. Red Cell Antigens and Type II Hypersensitivity
30. Immune Complexes and Type III Hypersensitivity
31. Type IV Hypersensitivity: Delayed Hypersensitivity
32. Organ Graft Rejection
33. Resistance to Tumors
34. Autoimmunity: General Principles
35. Organ-Specific Autoimmune Diseases
36. The Systemic Immunological Diseases
37. Primary Immunodeficiencies
38. Secondary Immunological Defects
39. Drugs and Other Agents That Affect the Immune System
40. The Evolution of the Immune System
41. Immunodiagnostic Techniques

Appendix 1: Annotated List Of Selected CD Molecules

Appendix 2: Some Selected Cytokines

Glossary