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Ultradian Rhythms from Molecules to Mind
A New Vision of Life
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5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism’s behavior to its environment has depended on one of life’s fundamental traits: biological rhythm generation. In virtually all light-sensitive organisms from cyanobacteria to humans, biological clocks adapt cyclic physiology to geophysical time with time-keeping properties in the circadian (24 h), ultradian (24 h) domains (Edmunds, 1988; Lloyd, 1998; Lloyd et al. , 2001; Lloyd and Murray, 2006; Lloyd, 2007; Pittendrigh, 1993; Sweeney and Hastings, 1960) By definition, all rhythms exhibit regular periodicities since they constitute a mechanism of timing. Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.


- A new vision integrating the Biology of Mind and Molecules

-A unique synthesis of the Arts, Sciences and Culture

- The New Sciences of Phychoscocial Genomics integrating genes, mind and brain

- The Biology Art, Beauty and Truth

- The Integration of Mind, Genes, Consciousness and Behaviour


Introduction: The Temporal organization of living systems from molecules to mind, D. Lloyd, E.L. Rossi, M.R. Roussel
Part 1 The Molecular-Genetic-Cellular Level
1. The Ultradian Clock (period about 40 min) in Saccharomyces cerevisiae, D. Lloyd, D.B. Murray, R.R. Klevecz, J. Wolf, H. Kuriyama; 2 ENOX proteins: copper hexahydrate-based ultradian oscillators of the cell’s biological clock, D.J.Morré, D.M. Morré; 3. Self-organized intracellular ultradian rhythms provide direct cell-cell communication, V.Y. Brodsky, D. Lloyd; 4. Phosphorylation dynamics in mammalian cells, D.A. Gilbert, K.D. Hammond; 5. Is there a mitochondrial clock?, M.A. Aon, S. Cortassa, B. O’Rourke
Part 2 Invertebrate Systems
6. Ultradian and circadian rhythms: experiments and models, B. Fuentes-Pardo, Carolina Barriga-Montoya, M.Lara Aparicio; 7. Ultradian lovesong rhythms in Drosophila, C.P. Kyriacou; 8. Mid-range ultradian rhythms in Drosophila and the circadian clock problem, H.B.Dowse; 9. Tidal rhythms, M.K. Chandrashekaran, V.K. Sharma
Part 3 The Neuroendocrineal and Developmental Level
10. Pulsatile hormonal signalling secretion: mechanisms, significance and evaluation, J.D.Veldhuis; 11. Ultradian rhythms as the dynamic signature of life, F.E. Yates, L.B. Yates; 12. Central and peripheral circadian oscillators: how the brain talks to the liver, U. Schibler
Part 4 Ultradian and Circadian Rhythms in Human Experience
13 Total sleep deprivation and cognitive performance: the case for multiple sources of variance, H. Babkoff, A. Goldstein, Z. Gil; 14. Ultradian Cognitive performance rhythms during sleep deprivation, C. LaJambe, F. Brown; 15. High Frequency EEG and Its Relationship to Cognitive Function, H. C. Sing; 16. Genes, sleep and dreams, S. Ribeiro; 17. A New Vision of Creative Experience: The Ultradian and Circadian Rhythms of Art, Beauty, and Truth, E. Rossi, K. Rossi; 18. Epilogue: A newvision of life, D. Lloyd, E. Rossi


ISBN-13: 9789048178520
Publisher: Springer (Springer Netherlands)
Publication date: October, 2010
Pages: 464
Weight: 706g
Availability: POD
Subcategories: General Practice, Neuroscience, Physiology
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