Recent advances in the understanding of the genetic, neurochemical, behavioral and cultural underpinnings of addiction have led to rapid advances in the understanding of addiction as a disease. In fact, advances in basic science and the development of new pharmacological and behavioral therapies associated with them are appearing faster than can be assimilated not only by clinical researchers but practitioners and policy makers as well. Translation of science-based addictions knowledge into improved prevention, assessment and treatment, and communication of these changes to researchers and practitioners are significant challenges to the field.The general aim of this book is to summarize current and potential linkages between advances in addiction science and innovations in clinical practice. Whilst this book is primarily focused on translation, it also encompasses some scientific advances that are relevant to dissemination, and the book is itself a tool for disseminating innovative thinking. The goal is to generate interest in application opportunities from both recent research and theoretical advances.
This book provides a much needed resource for translating current research into clinical practice. It focuses upon alcohol, tobacco, and substance abuse addictions. It addresses method of research and best dissemination techniques
TRANSLATION OF ADDICTIONS SCIENCE INTO PRACTICE: UPDATE AND FUTURE DIRECTIONS Peter M. Miller and David Kavanagh Preface Section title: GENETICS AND NEUROSCIENCE Chapter 1 The Interplay between Genotype and Gene Expression in Human Brain: What Can It Teach Us about Alcohol Dependence? (Dodd) Chapter 2 Common Genetic Influences on Antisociality and Addictions: Implications for Clinical Science and Practice (King) Chapter 3 Opioids, Pain and Addiction: Cause and Consequence (White and Hay) Chapter 4 Imbalance between Neuroexcitatory and Neuroinhibitory Amino Acids Causes Craving for Ethanol: From Animal to Human Studies (DeWitte) Chapter 5 Cannabis and the Brain: Implications of Recent Research (Sundram and Castle) Section title: PHARMACOTHERAPY Chapter 6 The Plasticity of Alcohol Addiction Suggests Novel Approaches to Pharmacological Intervention (Mulholland And Chandler) Chapter 7 Pharmacotherapies for the Treatment of Alcohol Dependence: Current and On-the-Horizon (Wright, Baros, Anton) Chapter 8 Agonist Treatment for Stimulant Abuse and Dependence (Herin and Grabowski) Chapter 9 Topiramate-Induced Neuromodulation of Cortico-Mesolimbic Dopamine: Implications for the Treatment of Nicotine and Alcohol Dependence (Johnson) Section title: PSYCHOLOGY AND SOCIOLOGY Chapter 10 Advances in the Scientific Study of Craving for Alcohol and Tobacco (MacKillop and Monti) Chapter 11 Advances in the Treatment of Craving for Alcohol and Tobacco (Monti and MacKillop) Chapter 12 Cognitive, Affective and Motivational Effects of Smoking (Powell and Dawkins) Chapter 13 Therapeutic Outcome Research in the Addictions (Wilbourne) Chapter 14 Implications of Research on Comorbidity for the Nature and Management of Substance Misuse (Mueser, Kavanagh, & Brunette) Chapter 15 The Role of Impulsive Personality Traits in the Initiation, Development and Treatment of Substance Misuse Problems (Dawe, Loxton, Gullo, Staiger, Kambouropoulos, Perdon, and Wood) Chapter 16 Translational Research Involving Adolescent Substance Abuse (Cornelius and Clark) Section title: PRACTICE AND POLICY Chapter 17 Dissemination of Evidence-Based Treatment into Substance Abuse Clinical Practice (Sorensen, Hettema, and Chen) Chapter 18 Alcohol Screening and Intervention in Medical and Surgical Settings (Stewart and Miller) Chapter 19 Internet-Based Interventions for Alcohol, Tobacco and Other Substances of Abuse (Cunningham) Chapter 20 Alcohol Use among Undergraduate Students: From Brief Interventions to Behavioral Economics (Henslee, Irons, and Correia) Chapter 21 Ethical and Policy Issues in the Translation of Genetic and Neuroscience Research on Addiction (Carter and Hall) Section Title: CONCLUSION Chapter 22 Pathways to Innovation in Addiction Practice (Kavanagh and Miller)