Main description:

Selenium has a long history of association with human health and disease. This essential trace element exerts its important biological role in selenoproteins. "Selenoproteins and Mimics" presents the latest developments in selenoproteins, their functional imitation by biomimetic chemistry and biology, and their relationship with human health and diseases. This book provides both the basic biology and biochemistry knowledge of selenoproteins, and sophisticated approaches for the development of new selenoprotein mimics. It's a valuable reference for researchers in biological technology, chemical syntheses, and medicine design.

Junqiu Liu is a professor at the State Key Lab of Supramolecular Structure and Materials, Jilin University, China. Guimin Luo is a professor at the Key Lab of Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, China.Ying Mu is a professor at the State Key Lab of Industrial Control Technology, Zhejiang University, and guest professor at the Key Lab of Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, China.

Contents:

Part 1 Selenoproteins: Glutathione Peroxidases.- Thyroid Hormone Deiodinases.-Thioredoxin Reductase.- Selenophosphate Synthetase.- Selenoprotein P.- Selenoprotein T.- Selenoprotein W.- Selenoprotein Biosynthesis.- Bioinformatics of Selenoproteins.-Selenoproteins and Atherosclerosis.- Selenoproteins and Brain Diseases.-Selenoproteins Thyroid Cancer.- Selenoproteinsand Selenium Speciation in Food.- Part 2. Selenoprotein Mimics: Synthetic Mimics of Selenoproteins.- Cycledextrin-based Mimics of Selenoproteins.- Semisynthsized Selenoproteins.- Selenium-containing Catalytic Antibodies.- Biosynthetic Mimics of Selenoproteins.- Nanoenzymes as Selenoprotein Mimics.- Selenoprotein Mimics and Diseases.