Main description:

The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph, with its leading authorship, presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It contains state-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer.

Contents:

Chapter 1: Metastasis: A Current Perspective
David T. Denhardt, Ann F. Chambers, Danny R. Welch Chapter 2: Control of Cell Motility during Tissue Invasion
James Varani Chapter 3: Cell adhesion and invasion during secondary tumor formation
Peter Gassmann, Joerg Haier and Garth L. Nicolson Chapter 4: Genes and Metastasis
Alison L. Allan and Ann F. Chambers Chapter 5: The evolution of diversity within tumors and metastases
Rakesh K. Singh and James E. Talmadge Chapter 6: Tumor angiogenesis, antiangiogenic therapy and anti-antiangiogenesis response
Mengfeng Li Chapter 7: Apoptosis and Cancer
Laszlo Kopper, Istvan Petak Chapter 8: Macrophages in Tumour Development and Metastasis
Alexandra Eichten, Karin E. de Visser, Lisa M. Coussens Chapter 9: Classical and alternative activation of macrophages: different pathways of macrophage-mediated tumor promotion
Jo Van Ginderachter, Yuanqing Liu, Nick Devoogdt, Wim Noel, Lea Brys, Gholamreza Hassanzadeh Gh., Geert Raes, Anja Geldhof, Alain Beschin, Hilde Revets and Patrick De Baetselier Chapter 10: Characterization of tumor-directed cellular immune responses in humans
Dirk Nagorsen, Vladia Monsurro and Francesco M. Marincola Chapter 11: Abnormal variation of the immune response as related to cancer
Gerhard R.F. Krueger and Maximilian Buja Chapter 12: Immunological Aspects of Marek's Disease Virus (MDV)-induced Lymphoma Progression
Mark S. Parcells and Shane C. Burgess Chapter 13: A Biodynamical Model of Human T-Cell Development and Pathology: Design, Testing and Validation
Michael E. Brandt, Gerhard R. F. Krueger and Guanyu Wang