Main description:

This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.

Contents:

Genetic Instability in Cancer. Oncogenesis and Telomerase Activity in Cancer. Cell Cycle Checkpoints in Cancer. Angiogenesis, Its Importance and Implication in Tumor Growth and Progression and in Anticancer Therapy: An Update. The Tumor Microenvironment and Metastasis. Apoptosis: A Regulatory Mechanism in Cancer. Cytoplasmic Signaling Circuitry: An Important Trait of Cancer. Cancer: An Overview of Risk Factors. Single Nucleotide Polymorphisms as Susceptibility Markers for Cancer. Dietary Phytochemicals in the Prevention and Therapy of Cancer: Modulation of Molecular Targets. Health Benefits and Preventive Effects of Common Beverages in Cancer. Cancer Chemotherapy. Non-Coding RNAs: The New Reins in Malignancies. Epigenetics in Cancer Prevention and Therapy: Role of Phytochemicals. Cancer Stem Cell: Current Understanding and Future Perspectives. Tumor Microenvironment and Cancer Stem Cells: Therapeutic Potential of Epigenetic Inhibitors to Target CSCs. Nanoparticles in Cancer Therapy. Cancer Immunotherapy: Extending New Horizons in Cancer Treatment.