1. Introduction Sally E. Rampersad; Part I. Design and Simulation: 2. Use of simulation and patient safety Douglas R. Thompson; 3. Using human-centered design to create a safer anesthesia workspace Eliot Grigg and Axel Roesler; Part II. QI Tools: 4. Preoccupation with failure: daily management system Aaron Dipzinski and Lynn D. Martin; 5. Lean vs. model for improvement Julianne Mendoza and David Buck; 6. Cause analysis Kristina A. Toncray; Part III. Reporting and Databases: 7. Reporting adverse events Rebecca Claure and Julianne Mendoza; 8. Learning from adverse events - Classification systems Imelda Tjia and Nathaniel Greene; 9. Databases and surgical quality improvement: pooling our data Manon Hache and Cindy B. Katz; Part IV. Putting Tools into Practice: 10. Medication safety at a pediatric hospital and Failure Modes Effects Analysis (FMEA) Lizabeth D Martin; 11. Reducing preventable clinical deterioration through the use of a safety surveillance team Joan S. Roberts and Wendy E. Murchie; Part V. People, Behavior, and Communication: 12. Nursing perspective in patient safety: quality, safety, advocacy Cindy B Katz; 13. Checklists and transitions of care: a how-to guide Daniel KW Low; 14. Communication tools to improve patient safety Kristina A. Toncray; 15. Winning hearts and minds: leading change Lynn D. Martin, Daniel K. W. Low and Sally E. Rampersad.