Main description:

New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

Contents:

1. Retinal Neurodegeneration in Experimental Glaucoma

Manuel Vidal-Sanz, Francisco J. Valiente-Soriano, Arturo Ortin-Martinez, Francisco M. Nadal-Nicolas, Manuel Jimenez-Lopez, Manuel Salinas-Navarro, Luis Alarcon-Martinez, Diego Garcia-Ayuso, Marcelino Aviles-Trigueros, Marta Agudo-Barriuso and Maria P. Villegas-Perez

2. Retinal Ganglion Cell Apoptotic Pathway in Glaucoma: Initiating and Downstream Mechanisms

Hani Levkovitch-Verbin

3. The Contribution of the Sclera and Lamina Cribrosa to the Pathogenesis of Glaucoma: Diagnostic and Treatment Implications

Harry A. Quigley

4. Autophagy Dysregulation and the Fate of Retinal Ganglion Cells in Glaucomatous Optic Neuropathy

Rossella Russo, Carlo Nucci, Maria Tiziana Corasaniti, Giacinto Bagetta and Luigi Antonio Morrone

5. Advances in Glaucoma Genetics

Yoichi Sakurada and Fumihiko Mabuchi

6. Oxidative Stress and Mitochondrial Failure in the Pathogenesis of Glaucoma Neurodegeneration

Maria D. Pinazo-Duran, Vicente Zanon-Moreno, Roberto Gallego-Pinazo and Jose J. Garcia-Medina

7. Macro- and Microglial Responses in the Fellow Eyes Contralateral to Glaucomatous Eyes

Ana I. Ramirez, Juan J. Salazar, Rosa de Hoz, Blanca Rojas, Beatriz I. Gallego, Elena Salobrar-Garcia, Francisco J. Valiente-Soriano, Alberto Trivino and Jose M. Ramirez

8. Retinal and Optic Nerve Changes in Glaucoma, From Animal Study to Clinical Implication

Shenton S. L. Chew, Alessandra Martins and Nicholas G Strouthidis

9. Lymphatic Drainage from the Eye: A New Target for Therapy

Yeni Yucel and Neeru Gupta

10. Retinal Ganglion Cell Dendrite Pathology and Synapse Loss: Implications for Glaucoma

Jessica Agostinone and Adriana Di Polo

11. MicroRNA Target Prediction in Glaucoma

Giovanni Luca Romano, Chiara Bianca Maria Platania, Stefano Forte, Salvatore Salomone, Filippo Drago and Claudio Bucolo

12. Stem Cell Approaches to Glaucoma, from Aqueous Outflow Modulation to Retinal Neuroprotection

Craig Pearson and Keith Martin

13. Natural Compounds and Retinal Ganglion Cell Neuroprotection

Luigi A. Morrone, Laura Rombola, Maria Tiziana Corasaniti, Giacinto Bagetta, Carlo Nucci and Rossella Russo

14. Rho Kinase Inhibitor AMA0526 Improves Surgical Outcome in a Rabbit Model of Glaucoma Filtration surgery

Sarah Van de Velde, Tine Van Bergen, Evelien Vandewalle, Nele Kindt, Karolien Castermans, Lieve Moons and Ingeborg Stalmans