Main description:

Neuroimaging in Parkinson's Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson's and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson's disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson's disease and in a number of related disorders.

Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson's disease and related disorders.

Contents:

Section I. Introduction 1. Parkinson's disease and related disorders: The pursuit for reliable readouts and the role of neuroimaging 2. Advances in magnetic resonance imaging 3. Advances in molecular neuromaging methodology

Section II. Clinical Applications in Parkinson's Disease 4. Dopaminergic molecular imaging in familial and idiopathic Parkinson's disease 5. Serotonergic molecular imaging in familial and idiopathic PD 6. Molecular imaging beyond dopamine and serotonin in familial and idiopathic Parkinson's disease 7. Structural MRI in familial and idiopathic PD 8. Functional MRI in familial and idiopathic PD 9. Molecular imaging in prodromal Parkinson's disease

Section III. Clinical Applications in Lewy Body Dementias 10. Molecular imaging evidence in favor or against PDD and DLB overlap 11. Magnetic resonance imaging in Parkinson's disease with mild cognitive impairment, Parkinson's disease dementia, and dementia with Lewy bodies

Section IV. Clinical Applications in Atypical Parkinsonian Disorders 12. Neuroimaging in multiple system atrophy 13. Neuroimaging in progressive supranuclear palsy 14. Neuroimaging in corticobasal syndrome

Section V. Clinical Applications in Other Movement Disorders 15. Molecular imaging in Huntington's disease 16. Magnetic resonance imaging in Huntington's disease 17. Neuroimaging in essential tremor 18. Neuroimaging in restless legs syndrome 19. Neuroimaging in dystonia 20. Demyelinating syndromes and movement disorders