Main description:

The purpose of this volume and Pediatric Nephrology Seminar IX from which it was created is to provide easy access to current concepts in the diagnosis and management of kidney diseases in the newborn. Complimentary to this purpose is the opportunity the Seminar structure gives me to invite those particularly interested in the subject chosen to come together, share experiences and ideas in an unhurried, unpressured atmosphere for four con tinuous days - an oasis for me and, I am told, also for the faculty and registrants. This year's subject choice is an expression of my perennial interest in the kidney of the newborn. A step back to view the steps forward reveals unwittingly intertwined associations and actions which now fall into focus. When I was just beginning my pediatric nephrology training with Sol Kaplan at Downstate in Brooklyn, we discussed Bob Usher's pioneering thought that there was something wrong with the kidneys of babies with RDS. Without really knowing what needed to be done, I started looking at the kidneys of those babies. Subsequently, Dick Day who was Chairman of the Department of Pedia trics there, stopped me in the hall, and asked me to come into his office. Glowing in quiet introspection, he extolled the joy of working with one's hands, then hurried away to his laboratory. He had been the Director of the Newborn Nursery at Babies Hospital before coming to Downstate, and (as I later found out) was trying to do something with oxygen electrodes.

Contents:

I The Fetus.- Intestinal Calcium Transport in Utero. Clinical Implications for the Newborn Infant.- Renal Response of the Fetus to Hypoxia.- Prenatal Diagnosis of Fetal Urinary Tract Abnormalities.- Congenital Nephropathies.- Highlights: Genetic Aspects of GU Congenital Anomalies and Renal Disease.- Panel Discussion.- II Low Birth Weight Infants.- Fluid and Electrolyte Management in Low Birth Weight Infants.- Renal Salt Excretion in the Low Birth Weight Infant.- Metabolic Bone Disease in Low Birth Weight Neonates.- Renal Thrombosis in Newborns.- Panel Discussion.- III Functional and Organic Evaluation of the Newborn.- Adaptation of the Kidney to Extrauterine Life.- Hydrogen Ion Balance in the Neonate.- Calcium, Vitamin D and Parathyroid Hormone Related Aspects in the Neonatal Period.- Highlights: Renal Concentrating Capacity in the Newborn.- Radio-Scintigraphic Evaluation of the Kidney in the Neonate.- Neonatal Ultrasound of the Urinary Tract.- Radiologic Evaluation of the Urinary Tract in the Neonate.- Panel Discussion.- IV Neonatal Pathological Situations.- Management of Massively Dilated Ureters in Children.- Fluid Balance in Sick Newborns.- Renal Function in Infants with Asphyxia and Respiratory Distress Syndrome.- The Oliguric Neonate.- Drugs and the Newborn Infant.- Management of Acute Renal Failure.- Panel Discussion.- V Workshops.- Workshop: General Discussion on Mineral Metabolism.- Workshop; Clinico-Pathologic Correlations.- Participants.- Author Index.