Main description:

This book presents the latest in mammary gland transgenesis, the exploitation of transgenic technology for the production of therapeutic proteins by routine or conventional methods. Following a section with an overview of all relevant methodologies, readers will find relevant information on the regulation of milk gene expression and bioreactor species such as cattle, rabbits and pigs.

Contents:

1. The Mammary Gland as a Bioreactor: A Personal Perspective.- 2. Introducing Genetic Information into Mammalian Embryos.- 3. The Factors of Tissue-Specific Expression of the Bovine ?-Casein Gene.- 4. Casein Gene-Based Mammary Gland-Specific Transgene Expression.- 5. Regulation of the Betalactoglobulin and Whey Acidic Protein Genes.- 6. Selection of Genes for Expression in Milk: The Case of the Human Erythropoietin Gene.- 7. Transgenesis in Rabbits.- 8. Transgenic Pigs as Bioreactors For Therapeutic Proteins.- 9. Transgenic Livestock as Bioreactors.- 10. Transgenic Dairy Cattle.- 11. Trying to Glimpse the Future.