This volume mainly describes the protocols for fabrication of liposomal drug delivery system, and consists of three parts, namely, the advances in liposome-based drug delivery system, the general protocols for fabrication of drug-loading liposomes, and the protocols for preparation of functionalized liposome-based drug delivery system. It unearths the formulation of drug-loading liposomes, describes the detailed operation of liposomal formulation, and demonstrates their potential applications. This handbook is targeted at scientists, research students, and young investigators in pharmaceutical enterprises.
The status and advances of liposomes in drug delivery. - Preparation of drug liposomes by thin-film hydration and homogenization. - Preparation of drug liposomes by reverse phase evaporation and freeze-thawing. - Preparation of drug liposomes by pH gradient and ammonium sulfate gradient methods. - Preparation of drug liposomes by sulfate gradient and nigericin Ionophore methods. - Preparation of drug liposomes by EDTA gradient methods. - CaP mediated insoluble drug loading for preparation of drug liposomes.