Main description:

This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today.

Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication.

Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems.

This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Contents:

PART I Glial-Neuronal Interactions in the Control of Hypothalamic Development

Chapter 1: The role of microglia in the developing hypothalamus - Deborah Kurrasch

PART II Glial-Neuronal Interactions in the Control of the Magnocellular Neuroendocrine System

Chapter 2: Structural dynamics in the hypothalamic-neurohypophysial system

Seiji Miyata

Chapter 3: Functional consequences of morphological plasticity in the adult hypothalamo-neurohypophysial system

Daniel L Voisin, Aude Panatier, Stephane H Oliet

Chapter 4: Synaptic scaling by astrocytes

Grant S.J. Gordon and Jaideep S. Bains

Chapter 5: Glial control of extrasynaptic receptor signaling in hypothalamic neurons

Javier Stern

PART III Glial-Neuronal Interactions in the Control of Metabolic Function

Chapter 6: Astrocytes in the brain control of systemic metabolism

O Le Thuc, T. Gruber, Matthias H. Tschoep, and Cristina Garcia-Caceres

Chapter 7: Astrocyte mediation of metabolic hormone effects on energy homeostasis

Julie A. Chowen

Chapter 8: Glia-neuron communication: Not a one-way street

Denise D. Belsham

PART IV: Glial-Neuronal Interactions in the Control of the Stress Response

Chapter 9: Neuronal-glial synaptic circuits in the hypothalamus

Juhee Haam, Zhiying Jiang, Jeffrey G. Tasker

PART V Glial-Neuronal Interactions in the Control of Reproductive Function

Chapter 10: Microglia, hormones, and behavior

Jaclyn M. Schwarz, Margaret M. McCarthy

Chapter 11: The role of astrocytes in estrogen positive feedback

Paul Micevych

PART VI Glial-Neuronal Interactions in the Control of the Blood-Brain Barrier

Chapter 12: Unveiling the importance of tanycytes in the control of the dialogue between the brain and the periphery

Vincent Prevot

Chapter 13: Tanycyte-neuronal interactions: Novel mechanisms for regulation of the thyroid axis

Ronald Lechan, Csaba Fekete