Main description:

The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease. This book is an indispensable tool tailor-made for specialists, non-specialists and the novice.

Contents:

Corresponding Authors; Preface;
1: Role of ACE, ACE2 and Neprilysin in the kidney, Mark C. Chappell;
2: ACE Inhibition in Heart Failure and Ischaemic Heart Disease, D. John Campbell;
3: Proteases of the Renin-Angiotensin System in Human Acute Pancreatitis, R. Pezzilli and L. Fantini;
4: The Renin-Angiotensin System in Pancreatic Stellate Cells: Implications in the Development and Progression of Type 2 Diabetes Mellitus, Seung-Hyun Ko, Yu-Bai Ahn, Ki-Ho Song and Kun-Ho Yoon;
5: Renin-Angiotensin System Proteases and the Cardiometabolic Syndrome: Pathopjysiological, Clinical and Therapeutic Implications, Guido Lastra, Camila Manrique and James R. Sowers;
6: The Role of the Renin-Angiotensin System in Hepatic Fibrosis, J.S. Lubel, F.J. Warner and P.W. Angus;
7: The Renin-Angiotensin System in the Breast, Gavin P. Vinson, Stewart Barker, John R. Puddefoot and Massoumeh Tahmasebi;
8: Role of Local Renin-Angiotensin System in the Carotid Body and in Diseases, Man Lung Fung and Po Sing Leung;
9: Bone Homeostasis: An Emerging Role for the Renin-Angiotensin System, C. Serina, H. Huang, K. Nguyen, L. Li, S. Hsu, M. Chen, N. Yu and M. Forwood;
10: The Renin-Angiotensin System and its Inhibitors in Human Cancers, Lucienne Juillerat-Jeanneret;
11: The Skeletal Muscle RAS in Health and Disease, David R. Woods;
12: Local Angiotensin Generation and AT2 Receptor Activation, Joep H.M. van Esch and A.H. Jan Danser;
13: ADAMs as Mediators of Angiotensin II Actions, A.M. Bourne and W. G. Thomas;
Index