Main description:

This new edition is a complete guide to medical pharmacology for students.

Beginning with an overview of pharmacological principles, the following sections cover drugs used to treat disorders in different systems of the body.

The next chapters discuss antimicrobial drugs and chemotherapy, and the book concludes with a section on miscellaneous drugs including immunosuppressant drugs, antiseptics, vitamins, and vaccines.

The eighth edition has been fully revised to provide the latest advances in the field. New drugs and the latest treatment guidelines have been added.

Most chapters conclude with an exercise in therapeutic decision making and topics are extensively referenced.

The text is highly illustrated with figures, charts and tables, and includes comprehensive appendices covering problem directed study, prescribing in pregnancy, and drugs in breastfeeding.

Key points

Comprehensive guide to medical pharmacology for students
Fully revised, eighth edition featuring many new drugs and latest treatment guidelines
Includes therapeutic decision making exercises
Previous edition (9789350259375) published in 2013

Contents:

Section 1 General Pharmacological Principles

Introduction, Routes of Drug Administration
Pharmacokinetics: Membrane Transport, Absorption and Distribution of Drugs
Pharmacokinetics: Metabolism and Excretion of Drugs, Kinetics of Elimination
Pharmacodynamics: Mechanism of Drug Action; Receptor Pharmacology
Aspects of Pharmacotherapy, Clinical Pharmacology and Drug Development
Adverse Drug Effects

Section 2 Drugs Acting on Autonomic Nervous System

Autonomic Nervous System: General Considerations

Cholinergic Transmission and Cholinergic Drugs
Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia
Adrenergic Transmission and Adrenergic Drugs
Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma

Section 3 Autacoids and Related Drugs

Histamine and Antihistaminics
5-Hydroxytryptamine, its Antagonists and Drug Therapy of Migraine
Prostaglandins, Leukotrienes (Eicosanoids) and Platelet Activating Factor
Nonsteroidal Anti Inflammatory Drugs and Antipyretic-Analgesics
Anti Rheumatoid and Antigout Drugs

Section 4 Respiratory System Drugs

Drugs for Cough and Bronchial Asthma

Section 5 Hormones and Related Drugs Introduction

Introduction

Anterior Pituitary Hormones
Thyroid Hormones and Thyroid Inhibitors
Insulin, Oral Antidiabetic Drugs and Glucagon
Corticosteroids
Androgens and Related Drugs, Drugs for Erectile Dysfunction
Estrogens, Progestins and Contraceptives
Oxytocin and Other Drugs Acting on Uterus
Hormones and Drugs Affecting Calcium Balance

Section 6 Drugs Acting on Peripheral (Somatic) Nervous System

Skeletal Muscle Relaxants
Local Anaesthetics

Section 7 Drugs Acting on Central Nervous System

General Anaesthetics
Ethyl and Methyl Alcohols
Sedative-Hypnotics
Antiepileptic Drugs
Antiparkinsonian Drugs
Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs
Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs
Opioid Analgesics and Antagonists
CN S Stimulants and Cognition Enhancers

Section 8 Cardiovascular Drugs

Cardiac Electrophysiological Considerations
Drugs Affecting Renin-Angiotensin System
Nitric Oxide and Vasoactive Peptide Signal Molecules
Cardiac Glycosides and Drugs for Heart Failure
Antiarrhythmic Drugs
Antianginal and Other Anti-ischaemic Drugs
Antihypertensive Drugs

Section 9 Drugs Acting on Kidney

Relevant Physiology of Urine Formation

Diuretics
Antidiuretics

Section 10 Drugs Affecting Blood and Blood Formation

Haematinics and Erythropoietin
Drugs Affecting Coagulation, Bleeding and Thrombosis
Hypolipidaemic Drugs

Section 11 Gastrointestinal Drugs

Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease
Antiemetic, Prokinetic and Digestant Drugs
Drugs for Constipation and Diarrhoea

Section 12 Antimicrobial Drugs

Antimicrobial Drugs: General Considerations
Sulfonamides, Cotrimoxazole and Quinolones
Beta-Lactam Antibiotics
Tetracyclines and Chloramphenicol (Broad-Spectrum Antibiotics)
Aminoglycoside Antibiotics
Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics
Antitubercular Drugs
Antileprotic Drugs
Antifungal Drugs
Antiviral Drugs (Non-retroviral)
Antiviral Drugs (Anti-retrovirus)
Antimalarial Drugs
Antiamoebic and Other Antiprotozoal Drugs
Anthelmintic Drugs

Section 13 Chemotherapy of Neoplastic Diseases

Anticancer Drugs

Section 14 Miscellaneous Drugs

Immunosuppressant Drugs
Drugs Acting on Skin and Mucous Membranes
Antiseptics, Disinfectants and Ectoparasiticides
Chelating Agents
Vitamins
Vaccines, Antisera and Immuneglobulins
Drug Interactions

Appendices

Appendix 1: Solution to Problem Directed Study

Appendix 2: Prescribing in Pregnancy

Appendix 3: Drugs in Breastfeeding

Appendix 4: Drugs and Fixed Dose Combinations Banned in India

Selected References for Further Reading

Index