Main description:

This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics.

Contents:

Chapter 1: Principles of pharmaceutical analysis in drug stability and chemical kineticsChapter 2: Guidelines for drug stability and stability testingChapter 3: Chemical kinetics and its applications in drug stabilityChapter 4: Methods and protocols for drug stability studiesChapter 5: Physical basis of degradation of pharmaceutical productsChapter 6: Role of microbiological degradation on drug stabilityChapter 7: Role of decomposition on drug stabilityChapter 8: Role of catalysis in drug stabilityChapter 9: Analytical techniques for the assessment of drug stabilityChapter 10: Stability of pharmaceutical productsChapter 11: Role of kinetic models in drug stabilityChapter 12: Photochemical basis of degradation of drug and drug stabilityChapter 13: Stability studies of portentous-compoundsChapter 14: Stability studies of extemporaneous pharmaceutical productsChapter 15: Stability studies of parenteral productsChapter 16: Stability studies of solid dosage formsChapter 17: Stability studies of vaccines